Research topic
Our research interest is the study of the pathophysiology of the vascular wall and the search for effective drugs to prevent and / or reverse cardiovascular damage. In recent years, our research has focused on the study of the relationship between excess weight and the development of cardiovascular disease (endothelial dusfunction, vascular remodeling, arterial stiffness), as well as to establish the molecular mechanisms involved in its development with a special focus on the renin-angiotensin system, oxidative stress, albuminuria and perivascular adipose tissue. A better understanding of these mechanisms will allow to develop and evaluate new drugs and design intervention strategies to prevent and / or slow the progression of cardiovascular disease associated with overweight and obesity. We have two main research topics, which are part of Challenge 1 "Health , demographic change and well-being" of the National Strategic Plan for Science and Technology and the social challenge of the European Union.
- Obesity and cardiovacular disease
- Albuminuria and cardiovascular diseaseWe are now working on following projects,
- Translational study of mechanisms involved in the development of arterial stiffness associated to obesity: new therapeutic strategies
- Translational research on mechanisms involved in the development of albuminuria and its relation to vascular dysfunction
- Study of natural products, drugs and diets useful in the treatment and prevention of cardiovascular damage associated to obesity and/or albuminuria